Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease

Huntington disease (HD) is a neurodegenerative disorder that is caused by a CAG repeat expansion in HTT. The length of this repeat, however, only explains a proportion of the variability in age of onset in patients. Genome-wide association studies have identified modifiers that contribute toward a p...

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Detalles Bibliográficos
Autores principales: Wright, Galen E B, Caron, Nicholas S, Ng, Bernard, Casal, Lorenzo, Casazza, William, Xu, Xiaohong, Ooi, Jolene, Pouladi, Mahmoud A, Mostafavi, Sara, Ross, Colin J D, Hayden, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530525/
https://www.ncbi.nlm.nih.gov/pubmed/32898862
http://dx.doi.org/10.1093/hmg/ddaa184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530525/
https://www.ncbi.nlm.nih.gov/pubmed/32898862
http://dx.doi.org/10.1093/hmg/ddaa184

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