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Mitochondrial dysfunction promotes aquaporin expression that controls hydrogen peroxide permeability and ferroptosis

Most anti-cancer agents and radiotherapy exert their therapeutic effects via the production of free radicals. Ferroptosis is a recently described cell death process that is accompanied by iron-dependent lipid peroxidation. Hydrogen peroxide (H(2)O(2)) has been reported to induce cell death. However,...

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Detalles Bibliográficos
Autores principales: Takashi, Yuko, Tomita, Kazuo, Kuwahara, Yoshikazu, Roudkenar, Mehryar Habibi, Roushandeh, Amaneh Mohammadi, Igarashi, Kento, Nagasawa, Taisuke, Nishitani, Yoshihiro, Sato, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530583/
https://www.ncbi.nlm.nih.gov/pubmed/33017631
http://dx.doi.org/10.1016/j.freeradbiomed.2020.09.027