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Mitochondrial dysfunction promotes aquaporin expression that controls hydrogen peroxide permeability and ferroptosis
Most anti-cancer agents and radiotherapy exert their therapeutic effects via the production of free radicals. Ferroptosis is a recently described cell death process that is accompanied by iron-dependent lipid peroxidation. Hydrogen peroxide (H(2)O(2)) has been reported to induce cell death. However,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530583/ https://www.ncbi.nlm.nih.gov/pubmed/33017631 http://dx.doi.org/10.1016/j.freeradbiomed.2020.09.027 |