Collateral Toxicity Limits the Evolution of Bacterial Release Factor 2 toward Total Omnipotence

When new genes evolve through modification of existing genes, there are often tradeoffs between the new and original functions, making gene duplication and amplification necessary to buffer deleterious effects on the original function. We have used experimental evolution of a bacterial strain lackin...

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Detalles Bibliográficos
Autores principales: Abdalaal, Hind, Pundir, Shreya, Ge, Xueliang, Sanyal, Suparna, Näsvall, Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530605/
https://www.ncbi.nlm.nih.gov/pubmed/32437534
http://dx.doi.org/10.1093/molbev/msaa129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530605/
https://www.ncbi.nlm.nih.gov/pubmed/32437534
http://dx.doi.org/10.1093/molbev/msaa129

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