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Collateral Toxicity Limits the Evolution of Bacterial Release Factor 2 toward Total Omnipotence
When new genes evolve through modification of existing genes, there are often tradeoffs between the new and original functions, making gene duplication and amplification necessary to buffer deleterious effects on the original function. We have used experimental evolution of a bacterial strain lackin...
Autores principales: | Abdalaal, Hind, Pundir, Shreya, Ge, Xueliang, Sanyal, Suparna, Näsvall, Joakim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530605/ https://www.ncbi.nlm.nih.gov/pubmed/32437534 http://dx.doi.org/10.1093/molbev/msaa129 |
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