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Gene Loss Predictably Drives Evolutionary Adaptation

Loss of gene function is common throughout evolution, even though it often leads to reduced fitness. In this study, we systematically evaluated how an organism adapts after deleting genes that are important for growth under oxidative stress. By evolving, sequencing, and phenotyping over 200 yeast li...

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Detalles Bibliográficos
Autores principales: Helsen, Jana, Voordeckers, Karin, Vanderwaeren, Laura, Santermans, Toon, Tsontaki, Maria, Verstrepen, Kevin J, Jelier, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530610/
https://www.ncbi.nlm.nih.gov/pubmed/32658971
http://dx.doi.org/10.1093/molbev/msaa172