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Gene Loss Predictably Drives Evolutionary Adaptation
Loss of gene function is common throughout evolution, even though it often leads to reduced fitness. In this study, we systematically evaluated how an organism adapts after deleting genes that are important for growth under oxidative stress. By evolving, sequencing, and phenotyping over 200 yeast li...
Autores principales: | Helsen, Jana, Voordeckers, Karin, Vanderwaeren, Laura, Santermans, Toon, Tsontaki, Maria, Verstrepen, Kevin J, Jelier, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530610/ https://www.ncbi.nlm.nih.gov/pubmed/32658971 http://dx.doi.org/10.1093/molbev/msaa172 |
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