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Sclerostin antibody stimulates periodontal regeneration in large alveolar bone defects

Destruction of the alveolar bone in the jaws can occur due to periodontitis, trauma or following tumor resection. Common reconstructive therapy can include the use of bone grafts with limited predictability and efficacy. Romosozumab, approved by the FDA in 2019, is a humanized sclerostin-neutralizin...

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Detalles Bibliográficos
Autores principales: Yao, Yao, Kauffmann, Frederic, Maekawa, Shogo, Sarment, Lea V., Sugai, James V., Schmiedeler, Caroline A., Doherty, Edward J., Holdsworth, Gill, Kostenuik, Paul J., Giannobile, William V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530715/
https://www.ncbi.nlm.nih.gov/pubmed/33004873
http://dx.doi.org/10.1038/s41598-020-73026-y