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FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells

Physiologically, MYC levels must be precisely set to faithfully amplify the transcriptome, but in cancer MYC is quantitatively misregulated. Here, we study the variation of MYC amongst single primary cells (B-cells and murine embryonic fibroblasts, MEFs) for the repercussions of variable cellular MY...

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Detalles Bibliográficos
Autores principales: Zheng, Ying, Dubois, Wendy, Benham, Craig, Batchelor, Eric, Levens, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530719/
https://www.ncbi.nlm.nih.gov/pubmed/33005010
http://dx.doi.org/10.1038/s42003-020-01264-x