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FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells
Physiologically, MYC levels must be precisely set to faithfully amplify the transcriptome, but in cancer MYC is quantitatively misregulated. Here, we study the variation of MYC amongst single primary cells (B-cells and murine embryonic fibroblasts, MEFs) for the repercussions of variable cellular MY...
Autores principales: | Zheng, Ying, Dubois, Wendy, Benham, Craig, Batchelor, Eric, Levens, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530719/ https://www.ncbi.nlm.nih.gov/pubmed/33005010 http://dx.doi.org/10.1038/s42003-020-01264-x |
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