Exosomal miR‐1255b‐5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial‐to‐mesenchymal transition

Cancer cells undergo epithelial‐to‐mesenchymal transition (EMT) in response to hypoxia. Exosomes produced in tumor microenvironments carry microRNAs (miRNAs) that affect proliferation, metastasis, and EMT. Hypoxic regulation of EMT is associated with telomerase content and stability, but the underly...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xue, Bai, Jian, Yin, Hang, Long, Long, Zheng, Zhewen, Wang, Qingqing, Chen, Fengxia, Yu, Xiaoyan, Zhou, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530775/
https://www.ncbi.nlm.nih.gov/pubmed/32679610
http://dx.doi.org/10.1002/1878-0261.12765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530775/
https://www.ncbi.nlm.nih.gov/pubmed/32679610
http://dx.doi.org/10.1002/1878-0261.12765

Ejemplares similares