Cargando…
Exosomal miR‐1255b‐5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial‐to‐mesenchymal transition
Cancer cells undergo epithelial‐to‐mesenchymal transition (EMT) in response to hypoxia. Exosomes produced in tumor microenvironments carry microRNAs (miRNAs) that affect proliferation, metastasis, and EMT. Hypoxic regulation of EMT is associated with telomerase content and stability, but the underly...
Autores principales: | Zhang, Xue, Bai, Jian, Yin, Hang, Long, Long, Zheng, Zhewen, Wang, Qingqing, Chen, Fengxia, Yu, Xiaoyan, Zhou, Yunfeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530775/ https://www.ncbi.nlm.nih.gov/pubmed/32679610 http://dx.doi.org/10.1002/1878-0261.12765 |
Ejemplares similares
-
Retraction Statement: Exosomal miR‐1255b‐5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial‐to‐mesenchymal transition
Publicado: (2023) -
Human telomerase reverse transcriptase promotes the epithelial to mesenchymal transition in lung cancer cells by enhancing c-MET upregulation
por: Prasad, Ram Raj, et al.
Publicado: (2021) -
Telomerase reverse transcriptase and neurodegenerative diseases
por: Yu, Xin, et al.
Publicado: (2023) -
Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
por: Maida, Yoshiko, et al.
Publicado: (2015) -
Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells
por: El-Badawy, Ahmed, et al.
Publicado: (2018)