Clearance of therapy‐induced senescent tumor cells by the senolytic ABT‐263 via interference with BCL‐X(L)–BAX interaction

Tumor cells undergo senescence in response to both conventional and targeted cancer therapies. The induction of senescence in response to cancer therapy can contribute to unfavorable patient outcomes, potentially including disease relapse. This possibiliy is supported by our findings that tumor cell...

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Detalles Bibliográficos
Autores principales: Saleh, Tareq, Carpenter, Valerie J., Tyutyunyk‐Massey, Liliya, Murray, Graeme, Leverson, Joel D., Souers, Andrew J., Alotaibi, Moureq R., Faber, Anthony C., Reed, Jason, Harada, Hisashi, Gewirtz, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530780/
https://www.ncbi.nlm.nih.gov/pubmed/32652830
http://dx.doi.org/10.1002/1878-0261.12761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530780/
https://www.ncbi.nlm.nih.gov/pubmed/32652830
http://dx.doi.org/10.1002/1878-0261.12761

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