Cargando…

Platelets are recruited to hepatocellular carcinoma tissues in a CX3CL1‐CX3CR1 dependent manner and induce tumour cell apoptosis

The mechanisms and biological functions of migrating platelets in cancer remain largely unknown. Here, we analyzed platelet infiltration in hepatocellular carcinoma. We detected platelet extravasation in both mouse and human HCC tissues. CX3CL1 directly induced platelet migration, and hypoxia enhanc...

Descripción completa

Detalles Bibliográficos
Autores principales: Miao, Shuo, Lu, Meng, Liu, Yue, Shu, Dan, Zhu, Ying, Song, Wei, Ma, Yuanyuan, Ma, Rong, Zhang, Bixiang, Fang, Chao, Ming, Zhang‐Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530782/
https://www.ncbi.nlm.nih.gov/pubmed/32799418
http://dx.doi.org/10.1002/1878-0261.12783