Nonsense‐mediated decay factor SMG7 sensitizes cells to TNFα‐induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1

Nonsense‐mediated decay (NMD) proteins are responsible for the surveillance and degradation of aberrant RNAs. Suppressor with morphogenetic effect on genitalia 7 (SMG7) is an NMD complex protein and a regulator of tumor necrosis factor (TNF)‐induced extrinsic apoptosis; however, this unique function...

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Detalles Bibliográficos
Autores principales: Yang, Limeng, Kraft, Vanessa A. N., Pfeiffer, Susanne, Merl‐Pham, Juliane, Bao, Xuanwen, An, Yu, Hauck, Stefanie M., Schick, Joel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530794/
https://www.ncbi.nlm.nih.gov/pubmed/32602581
http://dx.doi.org/10.1002/1878-0261.12754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530794/
https://www.ncbi.nlm.nih.gov/pubmed/32602581
http://dx.doi.org/10.1002/1878-0261.12754

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