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Aberrantly elevated suprabasin in the bone marrow as a candidate biomarker of advanced disease state in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are preleukemic disorders characterized by clonal growth of mutant hematopoietic stem and progenitor cells. MDS are associated with proinflammatory signaling, dysregulated immune response, and cell death in the bone marrow (BM). Aging, autoinflammation and autoimmunit...

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Detalles Bibliográficos
Autores principales: Pribyl, Miroslav, Hubackova, Sona, Moudra, Alena, Vancurova, Marketa, Polackova, Helena, Stopka, Tomas, Jonasova, Anna, Bokorova, Radka, Fuchs, Ota, Stritesky, Jan, Salovska, Barbora, Bartek, Jiri, Hodny, Zdenek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530796/
https://www.ncbi.nlm.nih.gov/pubmed/32696549
http://dx.doi.org/10.1002/1878-0261.12768