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Protein-N-myristoylation-dependent phosphorylation of serine 13 of tyrosine kinase Lyn by casein kinase 1γ at the Golgi during intracellular protein traffic

Protein N-myristoylation of Src-family kinases (SFKs) is a critical co-translational modification to anchor the enzymes in the plasma membrane. Phosphorylation of SFKs is also an essential modification for regulating their enzymatic activities. In this study, we used Phos-tag SDS-PAGE to investigate...

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Detalles Bibliográficos
Autores principales: Kinoshita-Kikuta, Emiko, Utsumi, Toshihiko, Miyazaki, Aya, Tokumoto, Chiharu, Doi, Kyosuke, Harada, Haruna, Kinoshita, Eiji, Koike, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531007/
https://www.ncbi.nlm.nih.gov/pubmed/33004926
http://dx.doi.org/10.1038/s41598-020-73248-0