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TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma

BACKGROUND: Mesenchymal fibroblasts are ubiquitous cells that maintain the extracellular matrix of organs. Within the lung, airway and parenchymal fibroblasts are crucial for lung development and are altered with disease, but it has been difficult to understand their roles due to the lack of distinc...

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Detalles Bibliográficos
Autores principales: Clifford, Rachel L., Yang, Chen Xi, Fishbane, Nick, Patel, Jamie, MacIsaac, Julia L., McEwen, Lisa M., May, Sean T., Castellanos-Uribe, Marcos, Nair, Parameswaran, Obeidat, Ma’en, Kobor, Michael S., Knox, Alan J., Hackett, Tillie-Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531162/
https://www.ncbi.nlm.nih.gov/pubmed/33008450
http://dx.doi.org/10.1186/s13148-020-00931-4