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TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma
BACKGROUND: Mesenchymal fibroblasts are ubiquitous cells that maintain the extracellular matrix of organs. Within the lung, airway and parenchymal fibroblasts are crucial for lung development and are altered with disease, but it has been difficult to understand their roles due to the lack of distinc...
Autores principales: | Clifford, Rachel L., Yang, Chen Xi, Fishbane, Nick, Patel, Jamie, MacIsaac, Julia L., McEwen, Lisa M., May, Sean T., Castellanos-Uribe, Marcos, Nair, Parameswaran, Obeidat, Ma’en, Kobor, Michael S., Knox, Alan J., Hackett, Tillie-Louise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531162/ https://www.ncbi.nlm.nih.gov/pubmed/33008450 http://dx.doi.org/10.1186/s13148-020-00931-4 |
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