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C3: connect separate connected components to form a succinct disease module

BACKGROUND: Precise disease module is conducive to understanding the molecular mechanism of disease causation and identifying drug targets. However, due to the fragmentization of disease module in incomplete human interactome, how to determine connectivity pattern and detect a complete neighbourhood...

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Detalles Bibliográficos
Autores principales: Wang, Bingbo, Hu, Jie, Wang, Yajun, Zhang, Chenxing, Zhou, Yuanjun, Yu, Liang, Guo, Xingli, Gao, Lin, Chen, Yunru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531168/
https://www.ncbi.nlm.nih.gov/pubmed/33008305
http://dx.doi.org/10.1186/s12859-020-03769-y