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C3: connect separate connected components to form a succinct disease module
BACKGROUND: Precise disease module is conducive to understanding the molecular mechanism of disease causation and identifying drug targets. However, due to the fragmentization of disease module in incomplete human interactome, how to determine connectivity pattern and detect a complete neighbourhood...
Autores principales: | Wang, Bingbo, Hu, Jie, Wang, Yajun, Zhang, Chenxing, Zhou, Yuanjun, Yu, Liang, Guo, Xingli, Gao, Lin, Chen, Yunru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531168/ https://www.ncbi.nlm.nih.gov/pubmed/33008305 http://dx.doi.org/10.1186/s12859-020-03769-y |
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