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Room-temperature neutron and X-ray data collection of 3CL M(pro) from SARS-CoV-2

The replication of SARS-CoV-2 produces two large polyproteins, pp1a and pp1ab, that are inactive until cleavage by the viral chymotrypsin-like cysteine protease enzyme (3CL M(pro)) into a series of smaller functional proteins. At the heart of 3CL M(pro) is an unusual catalytic dyad formed by the sid...

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Detalles Bibliográficos
Autores principales: Kneller, Daniel W., Phillips, Gwyndalyn, Kovalevsky, Andrey, Coates, Leighton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531248/
https://www.ncbi.nlm.nih.gov/pubmed/33006576
http://dx.doi.org/10.1107/S2053230X20011814