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Room-temperature neutron and X-ray data collection of 3CL M(pro) from SARS-CoV-2
The replication of SARS-CoV-2 produces two large polyproteins, pp1a and pp1ab, that are inactive until cleavage by the viral chymotrypsin-like cysteine protease enzyme (3CL M(pro)) into a series of smaller functional proteins. At the heart of 3CL M(pro) is an unusual catalytic dyad formed by the sid...
Autores principales: | Kneller, Daniel W., Phillips, Gwyndalyn, Kovalevsky, Andrey, Coates, Leighton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531248/ https://www.ncbi.nlm.nih.gov/pubmed/33006576 http://dx.doi.org/10.1107/S2053230X20011814 |
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