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Dynamical modeling predicts an inflammation-inducible CXCR7+ B cell precursor with potential implications in lymphoid blockage pathologies

BACKGROUND: The blockage at the early B lymphoid cell development pathway within the bone marrow is tightly associated with hematopoietic and immune diseases, where the disruption of basal regulatory networks prevents the continuous replenishment of functional B cells. Dynamic computational models m...

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Detalles Bibliográficos
Autores principales: Enciso, Jennifer, Mendoza, Luis, Álvarez-Buylla, Elena R., Pelayo, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531334/
https://www.ncbi.nlm.nih.gov/pubmed/33062419
http://dx.doi.org/10.7717/peerj.9902