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Dynamical modeling predicts an inflammation-inducible CXCR7+ B cell precursor with potential implications in lymphoid blockage pathologies
BACKGROUND: The blockage at the early B lymphoid cell development pathway within the bone marrow is tightly associated with hematopoietic and immune diseases, where the disruption of basal regulatory networks prevents the continuous replenishment of functional B cells. Dynamic computational models m...
Autores principales: | Enciso, Jennifer, Mendoza, Luis, Álvarez-Buylla, Elena R., Pelayo, Rosana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531334/ https://www.ncbi.nlm.nih.gov/pubmed/33062419 http://dx.doi.org/10.7717/peerj.9902 |
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