Global RNA editome landscape discovers reduced RNA editing in glioma: loss of editing of gamma-amino butyric acid receptor alpha subunit 3 (GABRA3) favors glioma migration and invasion

BACKGROUND: Gliomas are the most common and lethal type of intracranial tumors. With the current treatment regime, the median survival of patients with grade IV glioma (glioblastoma/GBM) remains at 14–16 months. RNA editing modifies the function and regulation of transcripts. The development of glia...

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Detalles Bibliográficos
Autores principales: Patil, Vikas, Pal, Jagriti, Mahalingam, Kulandaivelu, Somasundaram, Kumaravel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531343/
https://www.ncbi.nlm.nih.gov/pubmed/33062411
http://dx.doi.org/10.7717/peerj.9755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531343/
https://www.ncbi.nlm.nih.gov/pubmed/33062411
http://dx.doi.org/10.7717/peerj.9755

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