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Ig-like ACE2 protein therapeutics: A revival in development during the COVID-19 pandemic

While the potential therapeutic utility of angiotensin-converting enzyme 2 (ACE2) is well established, the clinical development of ACE2 drugs has been limited, likely due in part to the short half-life of the protein. In contrast, Ig-like ACE2 fusion proteins have exhibited greatly extended plasma h...

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Detalles Bibliográficos
Autores principales: Qian, Kewen, Hu, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531491/
https://www.ncbi.nlm.nih.gov/pubmed/32546047
http://dx.doi.org/10.1080/19420862.2020.1782600