Cargando…

Malignant tissues produce divergent antibody glycosylation of relevance for cancer gene therapy effectiveness

Gene therapy approaches now allow for the production of therapeutic antibodies by healthy or cancerous human tissues directly in vivo, and, with an increasing number of gene delivery methods available, the cell type for expression can be chosen. Yet, little is known about the biophysical changes int...

Descripción completa

Detalles Bibliográficos
Autores principales: Brücher, Dominik, Franc, Vojtech, Smith, Sheena N., Heck, Albert J. R., Plückthun, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531505/
https://www.ncbi.nlm.nih.gov/pubmed/32643525
http://dx.doi.org/10.1080/19420862.2020.1792084