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Malignant tissues produce divergent antibody glycosylation of relevance for cancer gene therapy effectiveness
Gene therapy approaches now allow for the production of therapeutic antibodies by healthy or cancerous human tissues directly in vivo, and, with an increasing number of gene delivery methods available, the cell type for expression can be chosen. Yet, little is known about the biophysical changes int...
Autores principales: | Brücher, Dominik, Franc, Vojtech, Smith, Sheena N., Heck, Albert J. R., Plückthun, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531505/ https://www.ncbi.nlm.nih.gov/pubmed/32643525 http://dx.doi.org/10.1080/19420862.2020.1792084 |
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