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Bivalent binding on cells varies between anti-CD20 antibodies and is dose-dependent

Based on their mechanism of action, two types of anti-CD20 antibodies are distinguished: Type I, which efficiently mediate complement-dependent cytotoxicity, and Type II, which instead are more efficient in inducing direct cell death. Several molecular characteristics of these antibodies have been s...

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Detalles Bibliográficos
Autores principales: Bondza, Sina, ten Broeke, Toine, Nestor, Marika, Leusen, Jeanette H. W., Buijs, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531561/
https://www.ncbi.nlm.nih.gov/pubmed/32744151
http://dx.doi.org/10.1080/19420862.2020.1792673