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An evaluation of instrument types for mass spectrometry-based multi-attribute analysis of biotherapeutics

Multi-attribute methods (MAM), based on proteolytic digestion followed by liquid chromatography-mass spectrometry analysis of proteolytic peptides, have gained substantial attention in the biopharmaceutical industry for quantifying a variety of quality attributes for therapeutic proteins. Most MAM d...

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Detalles Bibliográficos
Autores principales: Zhang, Zhongqi, Chan, Pik K., Richardson, Jason, Shah, Bhavana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531562/
https://www.ncbi.nlm.nih.gov/pubmed/32643531
http://dx.doi.org/10.1080/19420862.2020.1783062