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An evaluation of instrument types for mass spectrometry-based multi-attribute analysis of biotherapeutics
Multi-attribute methods (MAM), based on proteolytic digestion followed by liquid chromatography-mass spectrometry analysis of proteolytic peptides, have gained substantial attention in the biopharmaceutical industry for quantifying a variety of quality attributes for therapeutic proteins. Most MAM d...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531562/ https://www.ncbi.nlm.nih.gov/pubmed/32643531 http://dx.doi.org/10.1080/19420862.2020.1783062 |