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Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A

Tumor necrosis factor (TNF) and interleukin (IL)-17A are pleiotropic cytokines implicated in the pathogenesis of several autoimmune diseases including rheumatoid arthritis (RA) and psoriatic arthritis (PsA). JNJ-61178104 is a novel human anti-TNF and anti-IL-17A monovalent, bispecific antibody that...

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Detalles Bibliográficos
Autores principales: Zheng, Songmao, Shen, Fang, Jones, Brian, Fink, Damien, Geist, Brian, Nnane, Ivo, Zhou, Zhao, Hall, Jeff, Malaviya, Ravi, Ort, Tatiana, Wang, Weirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531573/
https://www.ncbi.nlm.nih.gov/pubmed/32544369
http://dx.doi.org/10.1080/19420862.2020.1770018