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Brief Report: Hydroxychloroquine does not induce hemolytic anemia or organ damage in a “humanized” G6PD A- mouse model

BACKGROUND: Hydroxychloroquine (HCQ) is widely used in the treatment of malaria, rheumatologic disease such as lupus, and most recently, COVID-19. These uses raise concerns about its safe use in the setting of glucose-6-phosphate dehydrogenase (G6PD) deficiency, especially as 11% of African American...

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Detalles Bibliográficos
Autores principales: Zuchelkowski, Benjamin E., Wang, Ling, Gingras, Sebastien, Xu, Qinzi, Yang, Minying, Triulzi, Darrell, Page, Grier P., Gordeuk, Victor R., Kim-Shapiro, Daniel B., Lee, Janet S., Gladwin, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531777/
https://www.ncbi.nlm.nih.gov/pubmed/33007039
http://dx.doi.org/10.1371/journal.pone.0240266