The glucosyltransferase activity of C. difficile Toxin B is required for disease pathogenesis

Enzymatic inactivation of Rho-family GTPases by the glucosyltransferase domain of Clostridioides difficile Toxin B (TcdB) gives rise to various pathogenic effects in cells that are classically thought to be responsible for the disease symptoms associated with C. difficile infection (CDI). Recent in...

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Detalles Bibliográficos
Autores principales: Bilverstone, Terry W., Garland, Megan, Cave, Rory J., Kelly, Michelle L., Tholen, Martina, Bouley, Donna M., Kaye, Philip, Minton, Nigel P., Bogyo, Matthew, Kuehne, Sarah A., Melnyk, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531778/
https://www.ncbi.nlm.nih.gov/pubmed/32960931
http://dx.doi.org/10.1371/journal.ppat.1008852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531778/
https://www.ncbi.nlm.nih.gov/pubmed/32960931
http://dx.doi.org/10.1371/journal.ppat.1008852

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