The mode of action of the Protein tyrosine phosphatase 1B inhibitor Ertiprotafib

Protein tyrosine phosphatase 1B (PTP1B) is a validated therapeutic target for the treatment of diabetes and obesity. Ertiprotafib is a PTP1B inhibitor that reached the clinical trial stage for the treatment of diabetes. Interestingly, Ertiprotafib reduces the melting temperature of PTP1B in differen...

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Detalles Bibliográficos
Autores principales: Kumar, Ganesan Senthil, Page, Rebecca, Peti, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531832/
https://www.ncbi.nlm.nih.gov/pubmed/33007022
http://dx.doi.org/10.1371/journal.pone.0240044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531832/
https://www.ncbi.nlm.nih.gov/pubmed/33007022
http://dx.doi.org/10.1371/journal.pone.0240044

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