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Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin

Three-dimensional (3D) chromatin organization plays a key role in regulating mammalian genome function; however, many of its physical features at the single-cell level remain underexplored. Here, we use live- and fixed-cell 3D super-resolution and scanning electron microscopy to analyze structural a...

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Detalles Bibliográficos
Autores principales: Miron, Ezequiel, Oldenkamp, Roel, Brown, Jill M., Pinto, David M. S., Xu, C. Shan, Faria, Ana R., Shaban, Haitham A., Rhodes, James D. P., Innocent, Cassandravictoria, de Ornellas, Sara, Hess, Harald F., Buckle, Veronica, Schermelleh, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531892/
https://www.ncbi.nlm.nih.gov/pubmed/32967822
http://dx.doi.org/10.1126/sciadv.aba8811