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Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin
Three-dimensional (3D) chromatin organization plays a key role in regulating mammalian genome function; however, many of its physical features at the single-cell level remain underexplored. Here, we use live- and fixed-cell 3D super-resolution and scanning electron microscopy to analyze structural a...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531892/ https://www.ncbi.nlm.nih.gov/pubmed/32967822 http://dx.doi.org/10.1126/sciadv.aba8811 |