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ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization

ELKS1 is a protein with proposed roles in regulated exocytosis in neurons and nuclear factor κB (NF-κB) signaling in cancer cells. However, how these two potential roles come together under physiological settings remain unknown. Since both regulated exocytosis and NF-κB signaling are determinants of...

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Detalles Bibliográficos
Autores principales: Lam, Hiu Yan, Arumugam, Surendar, Bae, Han Gyu, Wang, Cheng Chun, Jung, Sangyong, St. John, Ashley Lauren, Hong, Wanjin, Han, Weiping, Tergaonkar, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531903/
https://www.ncbi.nlm.nih.gov/pubmed/32937583
http://dx.doi.org/10.1126/sciadv.abb2497