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microRNA-139-3p Inhibits Malignant Behaviors of Laryngeal Cancer Cells via the KDM5B/SOX2 Axis and the Wnt/β-Catenin Pathway

BACKGROUND: Laryngeal cancer (LCA) is a common head and neck cancer. Lysine demethylase 5B (KDM5B) knockdown is expected as a new target for cancer prevention. We investigated the molecular mechanism of KDM5B in LCA. MATERIALS AND METHODS: The levels of KDM5B, microRNA (miR)-139-3p and high-mobility...

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Detalles Bibliográficos
Autores principales: Ma, Yifei, Chen, Zili, Yu, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532048/
https://www.ncbi.nlm.nih.gov/pubmed/33061611
http://dx.doi.org/10.2147/CMAR.S268871