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Targeted Inhibition of P4HB Promotes Cell Sensitivity to Gemcitabine in Urothelial Carcinoma of the Bladder

BACKGROUND: Bladder cancer (BC) is a common malignancy worldwide that accounts for 3% of global cancer diagnoses. Chemotherapy resistance limits the therapeutic effect of chemotherapeutic agents in patients with BC. Prolyl 4-hydroxylase, beta polypeptide (P4HB) is an endoplasmic reticulum (ER) chape...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoming, Bai, Yunjin, Zhang, Facai, Yang, Yubo, Feng, Dechao, Li, Ao, Yang, Zhiqiang, Li, Dengxiong, Tang, Yin, Wei, Xin, Wei, Wuran, Han, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532080/
https://www.ncbi.nlm.nih.gov/pubmed/33061438
http://dx.doi.org/10.2147/OTT.S267734