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Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems; however, evidence of their direct impact on cognitive functions is still lacking. We tested whether faecal microbio...

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Detalles Bibliográficos
Autores principales: D’Amato, Alfonsina, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Man, Angela L., Le Gall, Gwenaelle, Branca, Jacopo J. V., Ghelardini, Carla, Amedei, Amedeo, Bertelli, Eugenio, Regoli, Mari, Pacini, Alessandra, Luciani, Giulia, Gallina, Pasquale, Altera, Annalisa, Narbad, Arjan, Gulisano, Massimo, Hoyles, Lesley, Vauzour, David, Nicoletti, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532115/
https://www.ncbi.nlm.nih.gov/pubmed/33004079
http://dx.doi.org/10.1186/s40168-020-00914-w