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PQM-1 controls hypoxic survival via regulation of lipid metabolism

Animals have evolved responses to low oxygen conditions to ensure their survival. Here, we have identified the C. elegans zinc finger transcription factor PQM-1 as a regulator of the hypoxic stress response. PQM-1 is required for the longevity of insulin signaling mutants, but surprisingly, loss of...

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Detalles Bibliográficos
Autores principales: Heimbucher, Thomas, Hog, Julian, Gupta, Piyush, Murphy, Coleen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532158/
https://www.ncbi.nlm.nih.gov/pubmed/33009389
http://dx.doi.org/10.1038/s41467-020-18369-w