Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma

INTRODUCTION: Multiple myeloma (MM) is an extremely malignant and incurable hematological cancer. Increased expression of the c-Myc oncoprotein is closely associated with shorter overall survival of MM patients, implying that c-Myc is a potential therapeutic target. MAIN METHODS: We identified a pot...

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Detalles Bibliográficos
Autores principales: Yao, Ruosi, Xie, Yu, Sun, Xiaoyang, Zhang, Menghui, Zhou, Jian, Liu, Linlin, Gao, Jian, Xu, Kailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532311/
https://www.ncbi.nlm.nih.gov/pubmed/33061303
http://dx.doi.org/10.2147/DDDT.S264077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532311/
https://www.ncbi.nlm.nih.gov/pubmed/33061303
http://dx.doi.org/10.2147/DDDT.S264077

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