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Safety and Tolerability of Sodium Thiosulfate in Patients with an Acute Coronary Syndrome Undergoing Coronary Angiography: A Dose-Escalation Safety Pilot Study (SAFE-ACS)

BACKGROUND: In animal studies, hydrogen sulfide (H(2)S) has been shown to protect the heart from ischemia-reperfusion injury. This study evaluates the safety and tolerability of the H(2)S donor sodium thiosulfate (STS) in patients with acute coronary syndrome (ACS). METHODS: Eighteen patients, under...

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Detalles Bibliográficos
Autores principales: de Koning, Marie-Sophie L. Y., Assa, Solmaz, Maagdenberg, Carlijn G., van Veldhuisen, Dirk J., Pasch, Andreas, van Goor, Harry, Lipsic, Erik, van der Harst, Pim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532357/
https://www.ncbi.nlm.nih.gov/pubmed/33041696
http://dx.doi.org/10.1155/2020/6014915