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Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner

Sirtuin 3 (SIRT3) is a deacetylase involved in the development of many inflammation-related diseases including liver fibrosis. Withaferin A (WFA) is a bioactive constituent derived from the Withania somnifera plant, which has extensive pharmacological activities; however, little is known about the r...

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Detalles Bibliográficos
Autores principales: Gu, Jingya, Chen, Chang, Wang, Jue, Chen, Tingting, Yao, Wenjuan, Yan, Tingdong, Liu, Zhaoguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532400/
https://www.ncbi.nlm.nih.gov/pubmed/33029279
http://dx.doi.org/10.1155/2020/2452848