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Punicalagin Exerts Protective Effects against Ankylosing Spondylitis by Regulating NF-κB-TH17/JAK2/STAT3 Signaling and Oxidative Stress

BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by sacroiliitis and spinal rigidity of the axial joints. The role of oxidative stress and increased proinflammatory cytokines is well documented in AS pathogenesis. Punicalagin (2,3-hexahydroxydiphenoyl-gallagyl-...

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Detalles Bibliográficos
Autores principales: Feng, Xinzhe, Yang, Qinyuan, Wang, Chen, Tong, Wenwen, Xu, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532417/
https://www.ncbi.nlm.nih.gov/pubmed/33029510
http://dx.doi.org/10.1155/2020/4918239