Epigenetic silencing of CDKN1A and CDKN2B by SNHG1 promotes the cell cycle, migration and epithelial-mesenchymal transition progression of hepatocellular carcinoma

Enhanced SNHG1 (small nucleolar RNA host gene 1) expression has been found to play a critical role in the initiation and progression of hepatocellular carcinoma (HCC) with its detailed mechanism largely unknown. In this study, we show that SNHG1 promotes the HCC progression through epigenetically si...

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Detalles Bibliográficos
Autores principales: Li, Bei, Li, Ang, You, Zhen, Xu, Jingchang, Zhu, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532449/
https://www.ncbi.nlm.nih.gov/pubmed/33009370
http://dx.doi.org/10.1038/s41419-020-03031-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532449/
https://www.ncbi.nlm.nih.gov/pubmed/33009370
http://dx.doi.org/10.1038/s41419-020-03031-6

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