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An α(2)-adrenoceptor agonist: Dexmedetomidine induces protective cardiomyocyte hypertrophy through mitochondrial-AMPK pathway

Aims: Dexmedetomidine (Dex) as a highly selective α(2)-adrenoceptor agonist, was widely used anesthetic in perioperative settings, whether Dex induces cardiac hypertrophy during perioperative administration is unknown. Methods: The effects of Dex on cardiac hypertrophy were explored using the transv...

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Detalles Bibliográficos
Autores principales: Weng, Xiaojian, Liu, Hua, Zhang, Xiaodan, Sun, Qianqian, Li, Cheng, Gu, Minglu, Xu, Yanyifang, Li, Shitong, Li, Weiwei, Du, Jianer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532472/
https://www.ncbi.nlm.nih.gov/pubmed/33029088
http://dx.doi.org/10.7150/ijms.47598