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Novel combination of celecoxib and metformin improves the antitumor effect by inhibiting the growth of Hepatocellular Carcinoma

Objective: To explore the effect of COX-2 inhibitor celecoxib in combination with metformin on the prevention of Hepatocellular carcinoma (HCC) and the mechanisms involved. Methods: HCC cell lines and an HCC rat model were treated with celecoxib, metformin or a combination of both. Cell viability an...

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Detalles Bibliográficos
Autores principales: Hu, Jun-Wen, Chen, Bin, Zhang, Jie, Qi, Ya-Peng, Liang, Jia-Hao, Zhong, Jian-Hong, Xiang, Bang-De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532521/
https://www.ncbi.nlm.nih.gov/pubmed/33033527
http://dx.doi.org/10.7150/jca.47532