Cargando…
Novel combination of celecoxib and metformin improves the antitumor effect by inhibiting the growth of Hepatocellular Carcinoma
Objective: To explore the effect of COX-2 inhibitor celecoxib in combination with metformin on the prevention of Hepatocellular carcinoma (HCC) and the mechanisms involved. Methods: HCC cell lines and an HCC rat model were treated with celecoxib, metformin or a combination of both. Cell viability an...
Autores principales: | Hu, Jun-Wen, Chen, Bin, Zhang, Jie, Qi, Ya-Peng, Liang, Jia-Hao, Zhong, Jian-Hong, Xiang, Bang-De |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532521/ https://www.ncbi.nlm.nih.gov/pubmed/33033527 http://dx.doi.org/10.7150/jca.47532 |
Ejemplares similares
-
Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells
por: Cao, Nini, et al.
Publicado: (2020) -
Celecoxib Inhibits Hepatocellular Carcinoma Cell Growth and Migration by Targeting PNO1
por: Dai, Huijun, et al.
Publicado: (2019) -
Suppressing growth and invasion of human hepatocellular carcinoma cells by celecoxib through inhibition of cyclooxygenase-2
por: Tai, Yang, et al.
Publicado: (2019) -
Doxorubicin combined with celecoxib inhibits tumor growth of medullary thyroid carcinoma in xenografted mice
por: MENG, XIANYING, et al.
Publicado: (2014) -
Niosomal Delivery of Celecoxib and Metformin for Targeted Breast Cancer Treatment
por: Basheer, Haneen A., et al.
Publicado: (2023)