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KIAA0101 and UbcH10 interact to regulate non-small cell lung cancer cell proliferation by disrupting the function of the spindle assembly checkpoint

BACKGROUND: Chromosome mis-segregation caused by spindle assembly checkpoint (SAC) dysfunction during mitosis is an important pathogenic factor in cancer, and modulating SAC function has emerged as a potential novel therapy for non-small cell lung cancer (NSCLC). UbcH10 is considered to be associate...

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Detalles Bibliográficos
Autores principales: Lei, Han, Wang, Kun, Jiang, Tongying, Lu, Jingjing, Dong, Xue, Wang, Feilong, Li, Qiang, Zhao, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532574/
https://www.ncbi.nlm.nih.gov/pubmed/33008389
http://dx.doi.org/10.1186/s12885-020-07463-3